Some recent research shows evidence that grapefruit can react adversely with over 85 prescription medications. These interactions may occur with a wide variety of drugs and can result in life-threatening side effects, including abnormal heart rhythms, stomach bleeding, and kidney damage. Medications can interact with all forms of grapefruit, fresh, juice or frozen concentrate.
Don’t consume grapefruit or grapefruit juice if you’re taking any of these medications, unless advised to by your doctor:
• Statins (cholesterol-lowering drugs): lovastatin (Mevacor), atorvastatin (Lipitor), simvastatin (Zocor, Vytorin)
• Antihistamines: ebastine
• Calcium channel blockers (blood pressure drugs): nitrendipine, felodipine (Plendil), nifedipine (Adalat, Procardia)
• Psychiatric drugs: buspirone (BuSpar), triazolam (Halcion), carbamazepine (Tegretol), diazepam (Valium), midazolam (Versed), sertraline (Zoloft)
• Immunosuppressants: cyclosporine (Neoral), tacrolimus (Prograf)
• Pain medications: methadone • Erectile Dysfunction drugs: sildenafil (Viagra)
• HIV medication: saquinavir (Invirase) • Antiarrhythmics: amiodarone (Cordarone)
When you’re starting a new medication, it’s always a good idea to ask your doctor or pharmacist about any potential interactions between the new medication and foods, supplements, or other drugs you’re already taking.